Heart health
Heart health
Home/ Heart Health -Our Heart Heart Resources  Health News 
line
Heart health
My Heart Story Health Journal Health Resources
Site Map Disclaimer Contact
Heart Health
spacer
RSS
Subscribe to my RSS feed
Add to My Yahoo!
MY MSN
spacer spacer
Advertisement

HIV and AIDS HIV and AIDS Treatment

Drug Resistant HIV


Author:

Jason Leider, MD, PhD

Jacobi and North Central Bronx Hospitals

Medically Reviewed On: September 26, 2001

By Erica Heilman

HIV treatment has come a long way since the first reported case of AIDS in 1981. In the early days of AIDS, there were no drugs available to fight the immune deficiency that caused AIDS-related opportunistic infections.

Today there are a number of therapies available to people living with HIV. Many HIV drug therapies require carefully timed dosing schedules and multiple medications, and efficacy often depends on exacting adherence to these protocols. One concern among doctors and patients alike is drug resistance, which can be the result of poor adherence.

Below, Dr. Jason Leider, Director of the Adult HIV Program for Jacoby Hospital and North Central Bronx Hospital and the Health Center at Tremont, discusses the danger of drug resistance.

Could you give us a sense of the numbers of new HIV diagnoses per year, and the numbers of people currently being treated for HIV?
About 40,000 people are newly infected each year with HIV in the United States, and this number has actually stayed the same for the last few years.

There are about 900,000 people with HIV in the United States altogether right now. The majority are aware of their HIV status, but only perhaps 250,000 of these people are on consistent medications to help fight HIV.

What is drug-resistant HIV?
Drug-resistant HIV is HIV virus in a person that has partial to complete resistance to medications that are currently available for HIV treatment. In other words, the medications are no longer as effective or effective at all in treating the virus.

How does drug resistance happen?
The most common way it happens is when people miss medicine doses consistently. Often the virus will actually become resistant to the medicine, just the same way that, if you were given a treatment for an ear infection and didn't take the antibiotic consistently, missing a lot of doses, then often the infection doesn't respond as well to the antibiotic. You would then have to go on much more potent antibiotics and longer courses of treatment to cure the infection.

How many people who are currently in treatment are experiencing drug resistance?
In the study that we're doing up here at our hospitals, we're seeing about 30 percent of people with resistant virus. There's a report that's just coming out from UCLA. Their estimates are that in San Francisco, according to different analyses that they've used, by the year 2005, forty-two percent of all of the people in San Francisco who are HIV positive will not respond to current therapy.

Page 1 of 3 Next Page >>

RELATED PROGRAMS
Advertisement
This web site is updated continuously. Please, check back often for news.
  SbI