The patient above provides a good example of a common feeling many headache sufferers share: a fear that their pain may signify something much more ominous. And it is easy to understand these fears given the publicity cancer, infectious diseases, stroke, and other illnesses capable of inducing head pain have received. In 1988, the Headache Classification Committee of the International Headache Society (IHS) established a classification schema for headaches. It listed 13 major headache categories with more than a hundred subdivisions.
I will discuss in this article features of the primary headaches, important causes of secondary headaches, and the approach physicians usually take to explore the causes of headache in their patients, including laboratory testing.
Table 1 – IHS Headache Classification (summary)
| Migraine - with and without neurologic accompaniments |
| Tension-type headache - episodic and chronic |
| Cluster headache - episodic, chronic, and CPH |
| Exertional and other primary headache types |
| Post-traumatic headaches |
| Headache due to cerebrovascular disease - infarction, hemorrhage, arteritis |
| Headache due to altered intracranial pressure, intracranial infection, or tumor |
| Headache due to substance ingestion or withdrawal |
| Headache due to systemic infections |
| Headache due to metabolic disorders |
| Headache or facial pain due to disorder of cranial or facial structures |
| Neuralgias (nerve pain) and related conditions |
Primary and Secondary Headaches