JOHN HORN, PHARM.D: And so there's a fundamental difference between the oral and the topically applied drugs, just in the fact that with the oral you expose the whole body to the drug; with the topical you're really only exposing the area where the infection exists to the drug.
DAVID ESCHENBACH, MD: The intravaginal preparations usually have very few side effects, so they're quite well-tolerated. Occasionally, there will be an increased amount of irritation that goes on just from the preparation itself more related to the vehicle that it contains -- that contains it. The side effects of the oral therapy are, for the most part, nausea, some abdominal cramps and bloating are the most common.
ANNOUNCER: Whether women choose creams, suppositories, or oral treatment, they should also consider whether they want a short-acting treatment, or one that takes slightly longer. The right choice usually depends on the severity of the infection.
DAVID ESCHENBACH, MD: The topical therapy is anywhere from between one-time dose to a seven-day dose. The oral therapy is usually a one-time dose itself. The advantage of the one-day is it's obviously a one-time use and the efficacy is relatively high for people with mild symptoms. For the people with three- to seven-days, the advantage goes to people who have more moderate to severe symptoms or had recurrences before, where the one-time dose may not be enough to relieve symptoms.
ANNOUNCER: With all these choices, it's clear that treating a yeast infection isn't always as simple as it seems. So while women with past experience can treat themselves, anyone with doubts or with a first time infection should play it safe and talk to their doctor first.